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Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei

Every type of nucleic acid in cells undergoes programmed chemical post-transcriptional modification. Generally, modification enzymes use substrates derived from intracellular metabolism, one exception is queuine (q)/queuosine (Q), which eukaryotes obtain from their environment; made by bacteria and...

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Detalles Bibliográficos
Autores principales: Dixit, Sameer, Kessler, Alan C, Henderson, Jeremy, Pan, Xiaobei, Zhao, Ruoxia, D’Almeida, Gabriel Silveira, Kulkarni, Sneha, Rubio, Mary Anne T, Hegedűsová, Eva, Ross, Robert L, Limbach, Patrick A, Green, Brian D, Paris, Zdeněk, Alfonzo, Juan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682783/
https://www.ncbi.nlm.nih.gov/pubmed/34883512
http://dx.doi.org/10.1093/nar/gkab1204