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Regulation of PDGFR-β gene expression by targeting the G-vacancy bearing G-quadruplex in promoter

G-quadruplex is an essential element in gene transcription that serves as a promising drug target. Guanine-vacancy-bearing G-quadruplex (GVBQ) is a newly identified G-quadruplex that has distinct structural features from the canonical G-quadruplex. Potential GVBQ-forming motifs are widely distribute...

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Detalles Bibliográficos
Autores principales: Chen, Juan-nan, He, Yi-de, Liang, Hui-ting, Cai, Ting-ting, Chen, Qi, Zheng, Ke-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682790/
https://www.ncbi.nlm.nih.gov/pubmed/34850916
http://dx.doi.org/10.1093/nar/gkab1154