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Regulation of PDGFR-β gene expression by targeting the G-vacancy bearing G-quadruplex in promoter
G-quadruplex is an essential element in gene transcription that serves as a promising drug target. Guanine-vacancy-bearing G-quadruplex (GVBQ) is a newly identified G-quadruplex that has distinct structural features from the canonical G-quadruplex. Potential GVBQ-forming motifs are widely distribute...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682790/ https://www.ncbi.nlm.nih.gov/pubmed/34850916 http://dx.doi.org/10.1093/nar/gkab1154 |