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Symbiosis of Electrical and Metabolic Oscillations in Pancreatic β-Cells

Insulin is secreted in a pulsatile pattern, with important physiological ramifications. In pancreatic β-cells, which are the cells that synthesize insulin, insulin exocytosis is elicited by pulses of elevated intracellular Ca(2+) initiated by bursts of electrical activity. In parallel with these ele...

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Detalles Bibliográficos
Autores principales: Marinelli, Isabella, Fletcher, Patrick A., Sherman, Arthur S., Satin, Leslie S., Bertram, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682964/
https://www.ncbi.nlm.nih.gov/pubmed/34925070
http://dx.doi.org/10.3389/fphys.2021.781581