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Symbiosis of Electrical and Metabolic Oscillations in Pancreatic β-Cells
Insulin is secreted in a pulsatile pattern, with important physiological ramifications. In pancreatic β-cells, which are the cells that synthesize insulin, insulin exocytosis is elicited by pulses of elevated intracellular Ca(2+) initiated by bursts of electrical activity. In parallel with these ele...
Autores principales: | Marinelli, Isabella, Fletcher, Patrick A., Sherman, Arthur S., Satin, Leslie S., Bertram, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682964/ https://www.ncbi.nlm.nih.gov/pubmed/34925070 http://dx.doi.org/10.3389/fphys.2021.781581 |
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