A viral ubiquitination switch attenuates innate immunity and triggers nuclear import of virion DNA and infection

Antiviral defense and virus exclusion from the cell nucleus restrict foreign nucleic acid influx and infection. How the genomes of DNA viruses evade cytosolic pattern recognition and cross the nuclear envelope is incompletely understood. Here, we show that the virion protein V of adenovirus function...

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Detalles Bibliográficos
Autores principales: Bauer, Michael, Gomez-Gonzalez, Alfonso, Suomalainen, Maarit, Schilling, Nicolas, Hemmi, Silvio, Greber, Urs F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682987/
https://www.ncbi.nlm.nih.gov/pubmed/34919430
http://dx.doi.org/10.1126/sciadv.abl7150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682987/
https://www.ncbi.nlm.nih.gov/pubmed/34919430
http://dx.doi.org/10.1126/sciadv.abl7150

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