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A viral ubiquitination switch attenuates innate immunity and triggers nuclear import of virion DNA and infection
Antiviral defense and virus exclusion from the cell nucleus restrict foreign nucleic acid influx and infection. How the genomes of DNA viruses evade cytosolic pattern recognition and cross the nuclear envelope is incompletely understood. Here, we show that the virion protein V of adenovirus function...
Autores principales: | Bauer, Michael, Gomez-Gonzalez, Alfonso, Suomalainen, Maarit, Schilling, Nicolas, Hemmi, Silvio, Greber, Urs F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682987/ https://www.ncbi.nlm.nih.gov/pubmed/34919430 http://dx.doi.org/10.1126/sciadv.abl7150 |
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