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Repurposing ICG enables MR/PA imaging signal amplification and iron depletion for iron-overload disorders

Precise and noninvasive theranostic methods to quantify and deplete focal iron are of crucial importance for iron-overload disorders. Here, we developed an indocyanine green (ICG)–based imaging platform to reveal Fe(3+) in vitro and in vivo. The high sensitivity and specificity of ICG-Fe interaction...

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Detalles Bibliográficos
Autores principales: Lin, Huirong, Zhou, Yu, Wang, Jiaming, Wang, Huimeng, Yao, Tianhong, Chen, Hu, Zheng, Huili, Zhang, Yang, Ren, En, Jiang, Lai, Chu, Chengchao, Chen, Xiaoyuan, Mao, Jingsong, Wang, Fudi, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682994/
https://www.ncbi.nlm.nih.gov/pubmed/34919434
http://dx.doi.org/10.1126/sciadv.abl5862