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Cerebrospinal fluid CD4+ T cell infection in humans and macaques during acute HIV-1 and SHIV infection

HIV-1 replication within the central nervous system (CNS) impairs neurocognitive function and has the potential to establish persistent, compartmentalized viral reservoirs. The origins of HIV-1 detected in the CNS compartment are unknown, including whether cells within the cerebrospinal fluid (CSF)...

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Detalles Bibliográficos
Autores principales: Sharma, Vishakha, Creegan, Matthew, Tokarev, Andrey, Hsu, Denise, Slike, Bonnie M., Sacdalan, Carlo, Chan, Phillip, Spudich, Serena, Ananworanich, Jintanat, Eller, Michael A., Krebs, Shelly J., Vasan, Sandhya, Bolton, Diane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683024/
https://www.ncbi.nlm.nih.gov/pubmed/34874976
http://dx.doi.org/10.1371/journal.ppat.1010105