Cargando…

Cerebrospinal fluid CD4+ T cell infection in humans and macaques during acute HIV-1 and SHIV infection

HIV-1 replication within the central nervous system (CNS) impairs neurocognitive function and has the potential to establish persistent, compartmentalized viral reservoirs. The origins of HIV-1 detected in the CNS compartment are unknown, including whether cells within the cerebrospinal fluid (CSF)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharma, Vishakha, Creegan, Matthew, Tokarev, Andrey, Hsu, Denise, Slike, Bonnie M., Sacdalan, Carlo, Chan, Phillip, Spudich, Serena, Ananworanich, Jintanat, Eller, Michael A., Krebs, Shelly J., Vasan, Sandhya, Bolton, Diane L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683024/ https://www.ncbi.nlm.nih.gov/pubmed/34874976 http://dx.doi.org/10.1371/journal.ppat.1010105

Ejemplares similares

Distribution of Human Immunodeficiency Virus (HIV) Ribonucleic Acid in Cerebrospinal Fluid and Blood Is Linked to CD4/CD8 Ratio During Acute HIV
por: Chan, Phillip, et al.
Publicado: (2018)

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
por: Lal, Kerri G., et al.
Publicado: (2020)

Immunological, Cognitive, and Psychiatric Outcomes After Initiating Efavirenz- and Dolutegravir-based Antiretroviral Therapy During Acute Human Immunodeficiency Virus Infection
por: Chan, Phillip, et al.
Publicado: (2022)

Preferential and persistent impact of acute HIV-1 infection on CD4(+) iNKT cells in colonic mucosa
por: Paquin-Proulx, Dominic, et al.
Publicado: (2021)

Single-Cell Profiling of Latently SIV-Infected CD4(+) T Cells Directly Ex Vivo to Reveal Host Factors Supporting Reservoir Persistence
por: Tokarev, Andrey, et al.
Publicado: (2022)

Safety of lumbar puncture procedure in an international research setting during acute HIV infection
por: Chan, Phillip, et al.
Publicado: (2018)

Immunoprofiling Correlates of Protection Against SHIV Infection in Adjuvanted HIV-1 Pox-Protein Vaccinated Rhesus Macaques
por: Lu, Pinyi, et al.
Publicado: (2021)

Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection
por: Ananworanich, Jintanat, et al.
Publicado: (2016)

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV
por: Marshall, Vickie A., et al.
Publicado: (2018)

Individual Differences in CD4/CD8 T-Cell Ratio Trajectories and Associated Risk Profiles Modeled From Acute HIV Infection
por: Paul, Robert, et al.
Publicado: (2022)

Determinants of suboptimal CD4(+) T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV‐1 infection
por: Handoko, Ryan, et al.
Publicado: (2020)

Altered gene expression in asymptomatic SHIV-infected rhesus macaques (Macacca mulatta)
por: Carroll, Erica E, et al.
Publicado: (2006)

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
por: Shao, Wei, et al.
Publicado: (2009)

Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques
por: Hsu, Denise C., et al.
Publicado: (2018)

Preferential Infection of α4β7(+) Memory CD4(+) T Cells During Early Acute Human Immunodeficiency Virus Type 1 Infection
por: Tokarev, Andrey, et al.
Publicado: (2020)

Longitudinal analysis of the lung microbiota of cynomolgous macaques during long-term SHIV infection
por: Morris, Alison, et al.
Publicado: (2016)

Aikeqing decreases viral loads in SHIV89.6-infected Chinese rhesus macaques
por: Zhang, Gao-Hong, et al.
Publicado: (2016)

Expression of pIgR in the tracheal mucosa of SHIV/SIV-infected rhesus macaques
por: Li, Dong, et al.
Publicado: (2017)

Immunotherapy during the acute SHIV infection of macaques confers long-term suppression of viremia
por: Nishimura, Yoshiaki, et al.
Publicado: (2020)

Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies
por: Hora, Bhavna, et al.
Publicado: (2023)

The testis and epididymis are productively infected by SIV and SHIV in juvenile macaques during the post-acute stage of infection
por: Shehu-Xhilaga, Miranda, et al.
Publicado: (2007)

TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption
por: Hsu, Denise C., et al.
Publicado: (2021)

Switch to dolutegravir is well tolerated in Thais with HIV infection
por: Goh, Orlanda Q, et al.
Publicado: (2019)

Epigallocatechin-3-gallate local pre-exposure application prevents SHIV rectal infection of macaques
por: Liu, JB, et al.
Publicado: (2018)

Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques
por: Cadena, Anthony M., et al.
Publicado: (2021)

Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques
por: Walker-Sperling, Victoria E. K., et al.
Publicado: (2022)

Humoral Immunity to Primary Smallpox Vaccination: Impact of Childhood versus Adult Immunization on Vaccinia Vector Vaccine Development in Military Populations
por: Slike, Bonnie M., et al.
Publicado: (2017)

Neuropsychiatric outcomes before and after switching to dolutegravir-based therapy in an acute HIV cohort
por: Chan, Phillip, et al.
Publicado: (2020)

Brief Report: Safety and Tolerability of Inguinal Lymph Node Biopsy in Individuals With Acute HIV Infection in Thailand
por: Chintanaphol, Michelle, et al.
Publicado: (2018)

A MIV-150/Zinc Acetate Gel Inhibits SHIV-RT Infection in Macaque Vaginal Explants
por: Barnable, Patrick, et al.
Publicado: (2014)

Prophylactic and therapeutic effect of AZT/3TC in RT-SHIV infected Chinese-origin rhesus macaques
por: Wang, Wei, et al.
Publicado: (2014)

Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in newborn macaques
por: Hessell, Ann J., et al.
Publicado: (2016)

Therapeutic vaccination with IDLV-SIV-Gag results in durable viremia control in chronically SHIV-infected macaques
por: Blasi, Maria, et al.
Publicado: (2020)

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques
por: Wen, Jing, et al.
Publicado: (2021)

Two-dose emtricitabine/tenofovir alafenamide plus bictegravir prophylaxis protects macaques against SHIV infection
por: Bekerman, Elena, et al.
Publicado: (2020)

Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART
por: Obregon-Perko, Veronica, et al.
Publicado: (2021)

Circulating Plasma Exosomal Proteins of Either SHIV-Infected Rhesus Macaque or HIV-Infected Patient Indicates a Link to Neuropathogenesis
por: Chandra, Partha K., et al.
Publicado: (2023)

Antimicrobial prophylaxis does not improve post-surgical outcomes in SIV/SHIV-uninfected or SIV/SHIV-infected macaques (Macaca mulatta and Macaca fascicularis) based on a retrospective analysis
por: Moats, Cassandra, et al.
Publicado: (2022)

An Antiretroviral/Zinc Combination Gel Provides 24 Hours of Complete Protection against Vaginal SHIV Infection in Macaques
por: Kenney, Jessica, et al.
Publicado: (2011)

CD4(+) T Cells Modified by the Endoribonuclease MazF Are Safe and Can Persist in SHIV-infected Rhesus Macaques
por: Saito, Naoki, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bv3g3fq90oih685h4lpfe42d9i