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Binding-induced functional-domain motions in the Argonaute characterized by adaptive advanced sampling
Argonaute proteins in combination with short microRNA (miRNAs) can target mRNA molecules for translation inhibition or degradation and play a key role in many regulatory processes. The miRNAs act as guide RNAs that associate with Argonaute and the complementary mRNA target region. The complex format...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683029/ https://www.ncbi.nlm.nih.gov/pubmed/34843451 http://dx.doi.org/10.1371/journal.pcbi.1009625 |