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Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling

Serine ADP-ribosylation (ADPr) is a DNA damage-induced post-translational modification catalyzed by the PARP1/2:HPF1 complex. As the list of PARP1/2:HPF1 substrates continues to expand, there is a need for technologies to prepare mono- and poly-ADP-ribosylated proteins for biochemical interrogation....

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Detalles Bibliográficos
Autores principales: Mohapatra, Jugal, Tashiro, Kyuto, Beckner, Ryan L, Sierra, Jorge, Kilgore, Jessica A, Williams, Noelle S, Liszczak, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683085/
https://www.ncbi.nlm.nih.gov/pubmed/34874266
http://dx.doi.org/10.7554/eLife.71502