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Panitumumab Plus Fluorouracil and Folinic Acid Versus Fluorouracil and Folinic Acid Alone as Maintenance Therapy in RAS Wild-Type Metastatic Colorectal Cancer: The Randomized PANAMA Trial (AIO KRK 0212)

PURPOSE: The randomized PANAMA trial investigated the efficacy of panitumumab (Pmab) when added to maintenance therapy with fluorouracil and folinic acid (FU/FA) in patients with RAS wild-type metastatic colorectal cancer. METHODS: Following first-line induction therapy with six cycles of FU/FA and...

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Detalles Bibliográficos
Autores principales: Modest, Dominik Paul, Karthaus, Meinolf, Fruehauf, Stefan, Graeven, Ullrich, Müller, Lothar, König, Alexander Otto, Fischer von Weikersthal, Ludwig, Caca, Karel, Kretzschmar, Albrecht, Goekkurt, Eray, Haas, Siegfried, Kurreck, Annika, Stahler, Arndt, Held, Swantje, Jarosch, Armin, Horst, David, Reinacher-Schick, Anke, Kasper, Stefan, Heinemann, Volker, Stintzing, Sebastian, Trarbach, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683209/
https://www.ncbi.nlm.nih.gov/pubmed/34533973
http://dx.doi.org/10.1200/JCO.21.01332