The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms

Heparin, a naturally occurring glycosaminoglycan, has been found to have antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of COVID-19. To elucidate the mechanistic basis for the antiviral activity of heparin, we investigated the binding of...

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Detalles Bibliográficos
Autores principales: Paiardi, Giulia, Richter, Stefan, Oreste, Pasqua, Urbinati, Chiara, Rusnati, Marco, Wade, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683219/
https://www.ncbi.nlm.nih.gov/pubmed/34929169
http://dx.doi.org/10.1016/j.jbc.2021.101507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683219/
https://www.ncbi.nlm.nih.gov/pubmed/34929169
http://dx.doi.org/10.1016/j.jbc.2021.101507

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