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The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms
Heparin, a naturally occurring glycosaminoglycan, has been found to have antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of COVID-19. To elucidate the mechanistic basis for the antiviral activity of heparin, we investigated the binding of...
Autores principales: | Paiardi, Giulia, Richter, Stefan, Oreste, Pasqua, Urbinati, Chiara, Rusnati, Marco, Wade, Rebecca C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683219/ https://www.ncbi.nlm.nih.gov/pubmed/34929169 http://dx.doi.org/10.1016/j.jbc.2021.101507 |
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