Protein engineering strategies for rational immunogen design

Antibody immunodominance refers to the preferential and asymmetric elicitation of antibodies against specific epitopes on a complex protein antigen. Traditional vaccination approaches for rapidly evolving pathogens have had limited success in part because of this phenomenon, as elicited antibodies p...

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Detalles Bibliográficos
Autores principales: Caradonna, Timothy M., Schmidt, Aaron G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683408/
https://www.ncbi.nlm.nih.gov/pubmed/34921149
http://dx.doi.org/10.1038/s41541-021-00417-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683408/
https://www.ncbi.nlm.nih.gov/pubmed/34921149
http://dx.doi.org/10.1038/s41541-021-00417-1

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