Cargando…

Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

Capillary endothelial cells of the human blood–brain barrier (BBB) express high levels of P-glycoprotein (P-gp, encoded by ABCB1) and ABCG2 (encoded by ABCG2). However, little information is available regarding ATP-binding cassette transporters expressed at the zebrafish BBB, which has emerged as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Robey, Robert W., Robinson, Andrea N., Ali-Rahmani, Fatima, Huff, Lyn M., Lusvarghi, Sabrina, Vahedi, Shahrooz, Hotz, Jordan M., Warner, Andrew C., Butcher, Donna, Matta, Jennifer, Edmondson, Elijah F., Lee, Tobie D., Roth, Jacob S., Lee, Olivia W., Shen, Min, Tanner, Kandice, Hall, Matthew D., Ambudkar, Suresh V., Gottesman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683423/
https://www.ncbi.nlm.nih.gov/pubmed/34921178
http://dx.doi.org/10.1038/s41598-021-03500-8