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Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter
Capillary endothelial cells of the human blood–brain barrier (BBB) express high levels of P-glycoprotein (P-gp, encoded by ABCB1) and ABCG2 (encoded by ABCG2). However, little information is available regarding ATP-binding cassette transporters expressed at the zebrafish BBB, which has emerged as a...
Autores principales: | Robey, Robert W., Robinson, Andrea N., Ali-Rahmani, Fatima, Huff, Lyn M., Lusvarghi, Sabrina, Vahedi, Shahrooz, Hotz, Jordan M., Warner, Andrew C., Butcher, Donna, Matta, Jennifer, Edmondson, Elijah F., Lee, Tobie D., Roth, Jacob S., Lee, Olivia W., Shen, Min, Tanner, Kandice, Hall, Matthew D., Ambudkar, Suresh V., Gottesman, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683423/ https://www.ncbi.nlm.nih.gov/pubmed/34921178 http://dx.doi.org/10.1038/s41598-021-03500-8 |
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