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Functional and structural analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in the MYB oncoproteins associated with human cancer

MYB proteins are highly conserved DNA-binding domains (DBD) and mutations in MYB oncoproteins have been reported to cause aberrant and augmented cancer progression. Identification of MYB molecular biomarkers predictive of cancer progression can be used for improving cancer management. To address thi...

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Detalles Bibliográficos
Autores principales: Lim, Shu Wen, Tan, Kennet JunKai, Azuraidi, Osman Mohd, Sathiya, Maran, Lim, Ee Chen, Lai, Kok Song, Yap, Wai-Sum, Afizan, Nik Abd Rahman Nik Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683427/
https://www.ncbi.nlm.nih.gov/pubmed/34921182
http://dx.doi.org/10.1038/s41598-021-03624-x