Sitafloxacin reduces tumor necrosis factor alpha (TNFα) converting enzyme (TACE) phosphorylation and activity to inhibit TNFα release from lipopolysaccharide-stimulated THP-1 cells

Sepsis is a systemic reaction to an infection and resulting in excessive production of inflammatory cytokines and chemokines. It sometimes results in septic shock. The present study aimed to identify quinolone antibiotics that can reduce tumor necrosis factor alpha (TNFα) production and to elucidate...

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Detalles Bibliográficos
Autores principales: Sakamaki, Ippei, Fukushi, Michika, Ohashi, Wakana, Tanaka, Yukie, Itoh, Kazuhiro, Tomihara, Kei, Yamamoto, Yoshihiro, Iwasaki, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683466/
https://www.ncbi.nlm.nih.gov/pubmed/34921186
http://dx.doi.org/10.1038/s41598-021-03511-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683466/
https://www.ncbi.nlm.nih.gov/pubmed/34921186
http://dx.doi.org/10.1038/s41598-021-03511-5

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