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Genomic stability of mouse spermatogonial stem cells in vitro

Germline mutations underlie genetic diversity and species evolution. Previous studies have assessed the theoretical mutation rates and spectra in germ cells mostly by analyzing genetic markers and reporter genes in populations and pedigrees. This study reported the direct measurement of germline mut...

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Detalles Bibliográficos
Autores principales: Chuma, Shinichiro, Kanatsu-Shinohara, Mito, Katanaya, Ami, Hosokawa, Mihoko, Shinohara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683475/
https://www.ncbi.nlm.nih.gov/pubmed/34921203
http://dx.doi.org/10.1038/s41598-021-03658-1