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Knockdown of OLR1 weakens glycolytic metabolism to repress colon cancer cell proliferation and chemoresistance by downregulating SULT2B1 via c-MYC

Chemoresistance is one of the major problems of colon cancer treatment. In tumors, glycolytic metabolism has been identified to promote cell proliferation and chemoresistance. However, the molecular mechanisms underlying glycolytic metabolism and chemoresistance in colon cancer remains enigmatic. He...

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Detalles Bibliográficos
Autores principales: Zhao, Tiancheng, Li, Yezhou, Shen, Kexin, Wang, Quan, Zhang, Jiayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683511/
https://www.ncbi.nlm.nih.gov/pubmed/34921134
http://dx.doi.org/10.1038/s41419-021-04174-w