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Small molecule targeting amyloid fibrils inhibits Streptococcus mutans biofilm formation

Amyloid fibrils are important scaffold in bacterial biofilms. Streptococcus mutans is an established cariogenic bacteria dwelling within biofilms, and C123 segment of P1 protein is known to form amyloid fibrils in S. mutans biofilms, among which C3 segment could serve as a promising anti-amyloid tar...

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Detalles Bibliográficos
Autores principales: Chen, Yuanyuan, Cui, Guxin, Cui, Yuqi, Chen, Dongru, Lin, Huancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683520/
https://www.ncbi.nlm.nih.gov/pubmed/34919191
http://dx.doi.org/10.1186/s13568-021-01333-2