Increased Chlormethine-Induced DNA Double-Stranded Breaks in Malignant T Cells from Mycosis Fungoides Skin Lesions

Mycosis fungoides (MF) is a type of cutaneous T-cell lymphoma. Chlormethine (CL) is recommended as first-line therapy for MF, with a major purpose to kill tumor cells through DNA alkylation. To study the extent of treatment susceptibility and tumor specificity, we investigated the gene expression of...

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Detalles Bibliográficos
Autores principales: Chang, Yun-Tsan, Ignatova, Desislava, Hoetzenecker, Wolfram, Pascolo, Steve, Fassnacht, Christina, Guenova, Emmanuella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683611/
https://www.ncbi.nlm.nih.gov/pubmed/34977846
http://dx.doi.org/10.1016/j.xjidi.2021.100069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683611/
https://www.ncbi.nlm.nih.gov/pubmed/34977846
http://dx.doi.org/10.1016/j.xjidi.2021.100069

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