Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein

Pyruvate formate-lyase (PFL) is a glycyl radical enzyme (GRE) that converts pyruvate and coenzyme A into acetyl-CoA and formate in a reaction that is crucial to the primary metabolism of many anaerobic bacteria. The glycyl radical cofactor, which is posttranslationally installed by a radical S-adeno...

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Detalles Bibliográficos
Autores principales: Andorfer, Mary C., Backman, Lindsey R.F., Li, Phoebe L., Ulrich, Emily C., Drennan, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683613/
https://www.ncbi.nlm.nih.gov/pubmed/34801558
http://dx.doi.org/10.1016/j.jbc.2021.101423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683613/
https://www.ncbi.nlm.nih.gov/pubmed/34801558
http://dx.doi.org/10.1016/j.jbc.2021.101423

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