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Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein
Pyruvate formate-lyase (PFL) is a glycyl radical enzyme (GRE) that converts pyruvate and coenzyme A into acetyl-CoA and formate in a reaction that is crucial to the primary metabolism of many anaerobic bacteria. The glycyl radical cofactor, which is posttranslationally installed by a radical S-adeno...
Autores principales: | Andorfer, Mary C., Backman, Lindsey R.F., Li, Phoebe L., Ulrich, Emily C., Drennan, Catherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683613/ https://www.ncbi.nlm.nih.gov/pubmed/34801558 http://dx.doi.org/10.1016/j.jbc.2021.101423 |
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