miRNA-mediated control of exogenous OCT4 during mesenchymal-epithelial transition increases measles vector reprogramming efficiency

OCT4 is a key mediator of induced pluripotent stem cell (iPSC) reprogramming, but the mechanistic insights into the role of exogenous OCT4 and timelines that initiate pluripotency remain to be resolved. Here, using measles reprogramming vectors, we present microRNA (miRNA) targeting of exogenous OCT...

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Detalles Bibliográficos
Autores principales: Rallabandi, Ramya, Sharp, Brenna, Cruz, Conrad, Wang, Qi, Locsin, Alexis, Driscoll, Christopher B., Lee, Ella, Nelson, Tim, Devaux, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683617/
https://www.ncbi.nlm.nih.gov/pubmed/34977272
http://dx.doi.org/10.1016/j.omtm.2021.11.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683617/
https://www.ncbi.nlm.nih.gov/pubmed/34977272
http://dx.doi.org/10.1016/j.omtm.2021.11.012

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