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Filamin C regulates skeletal muscle atrophy by stabilizing dishevelled-2 to inhibit autophagy and mitophagy

FilaminC (Flnc) is a member of the actin binding protein family, which is preferentially expressed in the cardiac and skeletal muscle tissues. Although it is known to interact with proteins associated with myofibrillar myopathy, its unique role in skeletal muscle remains largely unknown. In this stu...

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Detalles Bibliográficos
Autores principales: Han, Shunshun, Cui, Can, Zhao, Xiyu, Zhang, Yao, Zhang, Yun, Zhao, Jing, Shen, Xiaoxu, He, Haorong, Wang, Jianping, Ma, Menggen, Li, Diyan, Zhu, Qing, Yin, Huadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683659/
https://www.ncbi.nlm.nih.gov/pubmed/34976434
http://dx.doi.org/10.1016/j.omtn.2021.11.022