A single injection of CM1021, a long half-life hepatocyte growth factor mimetic, increases liver mass in mice

Despite years of positive animal data, hepatocyte growth factor (HGF) has never been developed into a useful pharmaceutical, primarily due to its poor pharmacological properties. CM1021 is a fusion protein containing the K1 loop of HGF and the human IgG1 Fc region. The experiments described here dem...

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Detalles Bibliográficos
Autor principal: Kelly, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683692/
https://www.ncbi.nlm.nih.gov/pubmed/34977363
http://dx.doi.org/10.1016/j.bbrep.2021.101186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683692/
https://www.ncbi.nlm.nih.gov/pubmed/34977363
http://dx.doi.org/10.1016/j.bbrep.2021.101186

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