Heat shock factor 1 suppression induces spindle abnormalities and sensitizes cells to antimitotic drugs

BACKGROUND: Heat shock factor 1 (HSF1) is the master regulator of the heat shock response and supports malignant cell transformation. Recent work has shown that HSF1 can access the promoters of heat shock proteins (HSPs) and allow HSP expression during mitosis. It also acts as a mitotic regulator, c...

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Detalles Bibliográficos
Autores principales: Kuo, Hsiao-Hui, Su, Zhi-Rou, Chuang, Jing-Yuan, Yih, Ling-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684068/
https://www.ncbi.nlm.nih.gov/pubmed/34922589
http://dx.doi.org/10.1186/s13008-021-00075-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684068/
https://www.ncbi.nlm.nih.gov/pubmed/34922589
http://dx.doi.org/10.1186/s13008-021-00075-8

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