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Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing enterocolitis-induction protocol via alterations in butyrate and regulatory T cells

BACKGROUND: Necrotizing enterocolitis (NEC) remains a life-threatening disease in neonates. Numerous studies have shown a correlation between the intestinal microbiota and NEC, but the causal link remains unclear. This study aimed to demonstrate the causal role of gut microbiota in NEC and explore p...

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Detalles Bibliográficos
Autores principales: He, Yu, Du, Weixia, Xiao, Sa, Zeng, Benhua, She, Xiang, Liu, Dong, Du, Hua, Li, Luquan, Li, Fang, Ai, Qing, He, Junli, Song, Chao, Wei, Hong, Zhao, Xiaodong, Yu, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684079/
https://www.ncbi.nlm.nih.gov/pubmed/34922582
http://dx.doi.org/10.1186/s12967-021-03109-5