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Omega-3 mechanism of action in inflammation and endoplasmic reticulum stress in mononuclear cells from overweight non-alcoholic fatty liver disease participants: study protocol for the “Brazilian Omega Study” (BROS)—a randomized controlled trial

ABSTRACT: The low-grade inflammation is pivotal in obesity and its comorbidities; however, the inflammatory proteins are out of target for traditional drug therapy. Omega-3 (ω3) fatty acids can modulate the downstream signaling of Toll-like receptor (TLR) and tumor necrosis factor-α receptor (TNFα)...

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Detalles Bibliográficos
Autores principales: Batista, Ellencristina Silva, da Silva Rios, Thaiane, Muñoz, Vitor Rosetto, Jesus, Joyce Santos, Vasconcelos, Marcel Monteiro, da Cunha, Diogo Thimóteo, Marques-Rocha, Jose Luis, Nakandakari, Susana Castelo Branco Ramos, Lara, Roberta, da Silva, Adelino Sanchez Ramos, Pauli, José Rodrigo, Ropelle, Eduardo Rochete, Mekary, Rania Angelina, de Moura, Leandro Pereira, Camargo, Enilton Aparecido, Cintra, Dennys Esper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684080/
https://www.ncbi.nlm.nih.gov/pubmed/34922604
http://dx.doi.org/10.1186/s13063-021-05702-x