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Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift
BACKGROUND: Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in the liver parenchyma and tissue remodelling. Different cell types of the liver are known to play distinct roles in liver injury response. Hepato...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684102/ https://www.ncbi.nlm.nih.gov/pubmed/34920711 http://dx.doi.org/10.1186/s12864-021-08173-1 |