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Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift

BACKGROUND: Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in the liver parenchyma and tissue remodelling. Different cell types of the liver are known to play distinct roles in liver injury response. Hepato...

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Detalles Bibliográficos
Autores principales: Migdał, Maciej, Tralle, Eugeniusz, Abu Nahia, Karim, Bugajski, Łukasz, Kędzierska, Katarzyna Zofia, Garbicz, Filip, Piwocka, Katarzyna, Winata, Cecilia Lanny, Pawlak, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684102/
https://www.ncbi.nlm.nih.gov/pubmed/34920711
http://dx.doi.org/10.1186/s12864-021-08173-1