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Intramuscular uptake of tranexamic acid during haemorrhagic shock in a swine model

BACKGROUND: Tranexamic acid (TXA) reduce mortality in bleeding trauma patients, with greater effect if administered early. Serum concentrations above 10 µg/mL are considered sufficient to inhibit fibrinolysis. Normally administered intravenously (i.v.), TXA can also be administered intramuscularly (...

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Detalles Bibliográficos
Autores principales: Bakke, Håkon Kvåle, Fuskevåg, Ole Martin, Nielsen, Erik Waage, Dietrichs, Erik Sveberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684106/
https://www.ncbi.nlm.nih.gov/pubmed/34922577
http://dx.doi.org/10.1186/s13049-021-00983-2