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Intramuscular uptake of tranexamic acid during haemorrhagic shock in a swine model

BACKGROUND: Tranexamic acid (TXA) reduce mortality in bleeding trauma patients, with greater effect if administered early. Serum concentrations above 10 µg/mL are considered sufficient to inhibit fibrinolysis. Normally administered intravenously (i.v.), TXA can also be administered intramuscularly (...

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Detalles Bibliográficos
Autores principales:	Bakke, Håkon Kvåle, Fuskevåg, Ole Martin, Nielsen, Erik Waage, Dietrichs, Erik Sveberg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684106/ https://www.ncbi.nlm.nih.gov/pubmed/34922577 http://dx.doi.org/10.1186/s13049-021-00983-2

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