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Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model

BACKGROUND: Chemotherapy is frequently used in cancer treatment; however, it may cause adverse events, which must be managed. Reactive oxygen species (ROS) have been reported to be involved in the induction of intestinal mucositis and diarrhea, which are common side effects of treatment with fluorop...

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Detalles Bibliográficos
Autores principales: Yoneda, Junya, Nishikawa, Sachiko, Kurihara, Shigekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684148/
https://www.ncbi.nlm.nih.gov/pubmed/34922485
http://dx.doi.org/10.1186/s12885-021-09057-z