Integrative multi-omics identifies high risk multiple myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways

BACKGROUND: Despite significant therapeutic advances in improving lives of multiple myeloma (MM) patients, it remains mostly incurable, with patients ultimately becoming refractory to therapies. MM is a genetically heterogeneous disease and therapeutic resistance is driven by a complex interplay of...

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Detalles Bibliográficos
Autores principales: Ortiz-Estévez, María, Towfic, Fadi, Flynt, Erin, Stong, Nicholas, Jang, In Sock, Wang, Kai, Trotter, Matthew W. B., Thakurta, Anjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684160/
https://www.ncbi.nlm.nih.gov/pubmed/34922559
http://dx.doi.org/10.1186/s12920-021-01140-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684160/
https://www.ncbi.nlm.nih.gov/pubmed/34922559
http://dx.doi.org/10.1186/s12920-021-01140-5

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