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TKTL1 participated in malignant progression of cervical cancer cells via regulating AKT signal mediated PFKFB3 and thus regulating glycolysis

BACKGROUND: Cervical cancer (CC) is the second most common cancer among women with high morbidity and mortality. TKTL1 is a key protein in glucose metabolism in cancer cells and controls the pentose phosphate pathway (PPP). In this paper, we aim to explore whether TKTL1 can participate in the malign...

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Detalles Bibliográficos
Autores principales: Zhu, Yingping, Qiu, Yu, Zhang, Xueqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684167/
https://www.ncbi.nlm.nih.gov/pubmed/34922556
http://dx.doi.org/10.1186/s12935-021-02383-z