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BacMam virus-based surface display for HCV E2 glycoprotein induces strong cross-neutralizing antibodies and cellular immune responses in vaccinated mice

BACKGROUND: Despite recent advancements, limitations in the treatment and control of hepatitis C virus (HCV) infection reprioritized the studies for invention of an efficient HCV vaccine to elicit strong neutralizing antibodies (NAbs) and cellular responses. METHODS: Herein, we report molecular cons...

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Detalles Bibliográficos
Autores principales: Kord, Ebrahim, Roohvand, Farzin, Dubuisson, Jean, Vausselin, Thibaut, Nasr Azadani, Hosein, Keshavarz, Abolfazl, Nejati, Ahmad, Samimi-Rad, Katayoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684228/
https://www.ncbi.nlm.nih.gov/pubmed/34922563
http://dx.doi.org/10.1186/s13027-021-00407-x