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Anti-NOGO Antibody Neuroprotection in a Rat Model of NAION

PURPOSE: To evaluate the efficacy and mechanisms of anti-NOGO receptor monoclonal antibody 11C7mAb in a rat model of nonarteritic anterior ischemic optic neuropathy (rNAION). METHODS: The rNAION was induced in one eye of 20 Long-Evans rats, which were studied in 10 groups of two rats, each group con...

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Detalles Bibliográficos
Autores principales: Johnson, Mary A., Mehrabian, Zara, Guo, Yan, Ghosh, Joy, Brigell, Mitchell G., Bernstein, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684297/
https://www.ncbi.nlm.nih.gov/pubmed/34904998
http://dx.doi.org/10.1167/tvst.10.14.12