Cargando…

Anti-NOGO Antibody Neuroprotection in a Rat Model of NAION

PURPOSE: To evaluate the efficacy and mechanisms of anti-NOGO receptor monoclonal antibody 11C7mAb in a rat model of nonarteritic anterior ischemic optic neuropathy (rNAION). METHODS: The rNAION was induced in one eye of 20 Long-Evans rats, which were studied in 10 groups of two rats, each group con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johnson, Mary A., Mehrabian, Zara, Guo, Yan, Ghosh, Joy, Brigell, Mitchell G., Bernstein, Steven L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684297/ https://www.ncbi.nlm.nih.gov/pubmed/34904998 http://dx.doi.org/10.1167/tvst.10.14.12

Ejemplares similares

Topical Trabodenoson Is Neuroprotective in a Rodent Model of Anterior Ischemic Optic Neuropathy (rNAION)
por: Guo, Yan, et al.
Publicado: (2019)

Neuroprotection and Neuroregeneration Strategies Using the rNAION Model: Theory, Histology, Problems, Results and Analytical Approaches
por: Bernstein, Steven L., et al.
Publicado: (2022)

Biomarkers of lesion severity in a rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION)
por: Guo, Yan, et al.
Publicado: (2021)

Oligodendrocyte death, neuroinflammation, and the effects of minocycline in a rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION)
por: Mehrabian, Zara, et al.
Publicado: (2017)

Bilateral NAION and GPIbα gene
por: Lim, Christina S., et al.
Publicado: (2019)

Approaches to Potentiated Neuroprotective Treatment in the Rodent Model of Ischemic Optic Neuropathy
por: Mehrabian, Zara, et al.
Publicado: (2021)

Clinical Usefulness of Spectral-Domain Optical Coherence Tomography in Glaucoma and NAION
por: Lee, Tae Hee, et al.
Publicado: (2016)

Bilateral Sequential Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
por: Shir Yen, Wang, et al.
Publicado: (2021)

Bilateral Sequential NAION following Cataract Extraction: Case Report and Review of the Literature
por: Barequet, Dana, et al.
Publicado: (2014)

Estrogen is not neuroprotective in a rodent model of optic nerve stroke
por: Bernstein, Steven L., et al.
Publicado: (2007)

Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy
por: Guo, Yan, et al.
Publicado: (2016)

Experience-dependent expression of Nogo-A and Nogo receptor in the developing rat visual cortex
por: Wu, Xiaoying, et al.
Publicado: (2012)

Anti-Nogo-A antibody promotes brain function recovery after cardiopulmonary resuscitation in rats by reducing apoptosis
por: Wu, Qinqin, et al.
Publicado: (2020)

Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) Following a Hypovolemic Episode of Gastric Bleeding
por: Gkoumas, Evangelos, et al.
Publicado: (2020)

Targeting Therapeutic Antibodies to the CNS: a Comparative Study of Intrathecal, Intravenous, and Subcutaneous Anti-Nogo A Antibody Treatment after Stroke in Rats
por: Wahl, Anna-Sophia, et al.
Publicado: (2020)

Nogo-A and Nogo-66 receptor in amyotrophic lateral sclerosis
por: Teng, Felicia Yu Hsuan, et al.
Publicado: (2008)

Anti-Nogo-A antibodies prevent vascular leakage and act as pro-angiogenic factors following stroke
por: Rust, Ruslan, et al.
Publicado: (2019)

Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats
por: Shepherd, Daniel J., et al.
Publicado: (2016)

Risk factors and visual outcome of Non-Arteritic Ischemic Optic Neuropathy (NAION): Experience of a tertiary center in Kuwait
por: Behbehani, Raed, et al.
Publicado: (2021)

Evaluating the effectiveness of anti-Nogo treatment in spinal cord injuries
por: Mohammed, Raihan, et al.
Publicado: (2020)

Reduced Expression of Nogo-A Leads to Motivational Deficits in Rats
por: Enkel, Thomas, et al.
Publicado: (2014)

Peripapillary and Macular Flow Changes in Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) by Optical Coherence Tomography Angiography (OCT-A)
por: Liu, Juejun, et al.
Publicado: (2020)

Effects of Nogo-A and its receptor on the repair of sciatic nerve injury in rats
por: Jiang, Junjie, et al.
Publicado: (2021)

Non artheritic bilateral anterior ischaemic optic neuropathy (NAION) as devastating complication following Total Hip Arthroplasty: a case report
por: Manzotti, Alfonso, et al.
Publicado: (2019)

Intranasal delivery of full-length anti-Nogo-A antibody: A potential alternative route for therapeutic antibodies to central nervous system targets
por: Correa, Daphne, et al.
Publicado: (2023)

Nogo-A Neutralization Improves Graft Function in a Rat Model of Parkinson’s Disease
por: Seiler, Stefanie, et al.
Publicado: (2016)

Nogo-A and its functions beyond axonal inhibition: the controversial role of Nogo-A in Parkinson's disease
por: Seiler, Stefanie, et al.
Publicado: (2015)

Application of Antibodies to Neuronally Expressed Nogo-A Increases Neuronal Survival and Neurite Outgrowth
por: Nagaraj, Vini, et al.
Publicado: (2020)

Nogo-A and the regulation of neurotransmitter receptors
por: Tang, Bor Luen
Publicado: (2020)

Nogo receptor knockdown and ciliary neurotrophic factor attenuate diabetic retinopathy in streptozotocin-induced diabetic rats
por: Guo, Xiliang, et al.
Publicado: (2017)

Quantitative analysis of optical coherence tomographic angiography (OCT-A) in patients with non-arteritic anterior ischemic optic neuropathy (NAION) corresponds to visual function
por: Gaier, Eric D., et al.
Publicado: (2018)

Differential Conserted Activity Induced Regulation of Nogo Receptors (1–3), LOTUS and Nogo mRNA in Mouse Brain
por: Karlsson, Tobias E., et al.
Publicado: (2013)

Enhanced Nogo-P3 amplitudes of mothers compared with non-mother women during an emotional Go/Nogo task
por: Hayashi, Sayuri, et al.
Publicado: (2018)

Antibody-mediated inhibition of Nogo-A signaling promotes neurite growth in PC-12 cells
por: Yazdi, Iman K, et al.
Publicado: (2016)

Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury
por: Baya Mdzomba, Julius, et al.
Publicado: (2020)

Spatiotemporal expression of Nogo-66 receptor after focal cerebral ischemia
por: Cao, Yue, et al.
Publicado: (2016)

Upregulation of Nogo receptor expression induces apoptosis of retinal ganglion cells in diabetic rats
por: Liu, Xuezheng, et al.
Publicado: (2014)

Nogo-A aggravates oxidative damage in oligodendrocytes
por: Wang, Yang-Yang, et al.
Publicado: (2020)

Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA
por: Lin, Cheng Yung, et al.
Publicado: (2019)

Chinese Medicine's Intervention Effect on Nogo-A/NgR
por: Qin, Xiu-de, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_upq9bntddtf9ji4embnsnadrar