Prophylactic Knockdown of the miR-183/96/182 Cluster Ameliorates Pseudomonas aeruginosa–Induced Keratitis

PURPOSE: Previously, we demonstrated that miR-183/96/182 cluster (miR-183C) knockout mice exhibit decreased severity of Pseudomonas aeruginosa (PA)-induced keratitis. This study tests the hypothesis that prophylactic knockdown of miR-183C ameliorates PA keratitis indicative of a therapeutic potentia...

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Detalles Bibliográficos
Autores principales: McClellan, Sharon, Pitchaikannu, Ahalya, Wright, Robert, Bessert, Denise, Iulianelli, Mason, Hazlett, Linda D., Xu, Shunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684302/
https://www.ncbi.nlm.nih.gov/pubmed/34919120
http://dx.doi.org/10.1167/iovs.62.15.14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684302/
https://www.ncbi.nlm.nih.gov/pubmed/34919120
http://dx.doi.org/10.1167/iovs.62.15.14

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