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Heterologous prime-boost immunizations with chimpanzee adenoviral vectors elicit potent and protective immunity against SARS-CoV-2 infection

A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is urgently needed to tackle the COVID-19 global pandemic. Here, we describe the development of chimpanzee adenovirus serotypes 6 and 68 (AdC6 and AdC68) vector-based vaccine candidates expressing the full-...

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Detalles Bibliográficos
Autores principales: Liu, Jiaojiao, Xu, Kun, Xing, Man, Zhuo, Yue, Guo, Jingao, Du, Meng, Wang, Qi, An, Yaling, Li, Jinhe, Gao, Ping, Wang, Yihan, He, Furong, Guo, Yingying, Li, Mingxi, Zhang, Yuchao, Zhang, Linqi, Gao, George F., Dai, Lianpan, Zhou, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684349/
https://www.ncbi.nlm.nih.gov/pubmed/34923570
http://dx.doi.org/10.1038/s41421-021-00360-4