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Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function

The regulation and homeostasis of autophagy are essential for maintaining organ morphology and function. As a lysosomal membrane protein, the effect of Sidt2 on kidney structure and renal autophagy is still unknown. In this study, we found that the kidneys of Sidt2(−/−) mice showed changes in baseme...

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Detalles Bibliográficos
Autores principales: Geng, Meng-ya, Wang, Lizhuo, Song, Ying-ying, Gu, Jing, Hu, Xin, Yuan, Cheng, Yang, Meng, Pei, Wen-jun, Zhang, Yao, Gao, Jia-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684554/
https://www.ncbi.nlm.nih.gov/pubmed/34923568
http://dx.doi.org/10.1038/s41419-021-04453-6