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Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function
The regulation and homeostasis of autophagy are essential for maintaining organ morphology and function. As a lysosomal membrane protein, the effect of Sidt2 on kidney structure and renal autophagy is still unknown. In this study, we found that the kidneys of Sidt2(−/−) mice showed changes in baseme...
Autores principales: | Geng, Meng-ya, Wang, Lizhuo, Song, Ying-ying, Gu, Jing, Hu, Xin, Yuan, Cheng, Yang, Meng, Pei, Wen-jun, Zhang, Yao, Gao, Jia-lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684554/ https://www.ncbi.nlm.nih.gov/pubmed/34923568 http://dx.doi.org/10.1038/s41419-021-04453-6 |
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