Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1

BACKGROUND: Controversy over the benefits of antioxidants supplements in cancers persists for long. Using hepatocellular carcinoma (HCC) as a model, we investigated the effects of exogenous antioxidants N-acetylcysteine (NAC) and glutathione (GSH) on tumor formation and growth. METHODS: Multiple mou...

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Detalles Bibliográficos
Autores principales: Zhang, Vanilla Xin, Sze, Karen Man-Fong, Chan, Lo-Kong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chiu, Yung-Tuen, Lee, Eva, Husain, Abdullah, Huang, Hongyang, Tian, Lu, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684635/
https://www.ncbi.nlm.nih.gov/pubmed/34924003
http://dx.doi.org/10.1186/s13578-021-00731-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684635/
https://www.ncbi.nlm.nih.gov/pubmed/34924003
http://dx.doi.org/10.1186/s13578-021-00731-0

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