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Cervical cancer-derived exosomal miR-663b promotes angiogenesis by inhibiting vinculin expression in vascular endothelial cells

BACKGROUND: Angiogenesis provides essential nutrients and oxygen for tumor growth and has become the main mechanism of tumor invasion and metastasis. Exosomes are nanoscale membrane vesicles containing proteins, lipids, mRNA and microRNA (miRNA), which mediate intercellular communication and play an...

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Detalles Bibliográficos
Autores principales: You, Xuewu, Sun, Wenxiong, Wang, Ying, Liu, Xiaoli, Wang, Aihong, Liu, Lu, Han, Sai, Sun, Yu, Zhang, Junhua, Guo, Lingyu, Zhang, Youzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684657/
https://www.ncbi.nlm.nih.gov/pubmed/34923985
http://dx.doi.org/10.1186/s12935-021-02379-9