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Regulation of osteoblast autophagy based on PI3K/AKT/mTOR signaling pathway study on the effect of β-ecdysterone on fracture healing

OBJECTIVES: To investigate the effects of β-ecdysterone on fracture healing and the underlying mechanism. METHODS: MTT assay was used to detect the cell viability. AO/PI and flow cytometry assays were used to determine the apoptotic rate. The expression level of RunX2, ATG7 and LC3 was evaluated by...

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Detalles Bibliográficos
Autores principales: Tang, Yanghua, Mo, Yafeng, Xin, Dawei, Xiong, Zhenfei, Zeng, Linru, Luo, Gan, Cao, Yanguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684673/
https://www.ncbi.nlm.nih.gov/pubmed/34924000
http://dx.doi.org/10.1186/s13018-021-02862-z