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SUMO paralogue–specific functions revealed through systematic analysis of human knockout cell lines and gene expression data

The small ubiquitin-related modifiers (SUMOs) regulate nearly every aspect of cellular function, from gene expression in the nucleus to ion transport at the plasma membrane. In humans, the SUMO pathway has five SUMO paralogues with sequence homologies that range from 45% to 97%. SUMO1 and SUMO2 are...

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Detalles Bibliográficos
Autores principales: Bouchard, Danielle, Wang, Wei, Yang, Wei-Chih, He, Shuying, Garcia, Anthony, Matunis, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684707/
https://www.ncbi.nlm.nih.gov/pubmed/34232706
http://dx.doi.org/10.1091/mbc.E21-01-0031