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SUMO paralogue–specific functions revealed through systematic analysis of human knockout cell lines and gene expression data
The small ubiquitin-related modifiers (SUMOs) regulate nearly every aspect of cellular function, from gene expression in the nucleus to ion transport at the plasma membrane. In humans, the SUMO pathway has five SUMO paralogues with sequence homologies that range from 45% to 97%. SUMO1 and SUMO2 are...
Autores principales: | Bouchard, Danielle, Wang, Wei, Yang, Wei-Chih, He, Shuying, Garcia, Anthony, Matunis, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684707/ https://www.ncbi.nlm.nih.gov/pubmed/34232706 http://dx.doi.org/10.1091/mbc.E21-01-0031 |
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