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Hsf1 activation by proteotoxic stress requires concurrent protein synthesis

Heat shock factor 1 (Hsf1) activation is responsible for increasing the abundance of protein-folding chaperones and degradation machinery in response to proteotoxic conditions that give rise to misfolded or aggregated proteins. Here we systematically explored the link between concurrent protein synt...

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Detalles Bibliográficos
Autores principales: Tye, Blake W., Churchman, L. Stirling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684711/
https://www.ncbi.nlm.nih.gov/pubmed/34191586
http://dx.doi.org/10.1091/mbc.E21-01-0014