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Hsf1 activation by proteotoxic stress requires concurrent protein synthesis
Heat shock factor 1 (Hsf1) activation is responsible for increasing the abundance of protein-folding chaperones and degradation machinery in response to proteotoxic conditions that give rise to misfolded or aggregated proteins. Here we systematically explored the link between concurrent protein synt...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684711/ https://www.ncbi.nlm.nih.gov/pubmed/34191586 http://dx.doi.org/10.1091/mbc.E21-01-0014 |